Home - Reproductive Genetics - General Edition - PGTM-ChromSwift® Preimplantation Genetic Testing for Monogenic disorders
Precise detection and screening of embryos to blocking single-gene genetic diseases.
PGT-M is an IVF technology specifically for single-gene genetic diseases. If a couple has a single-gene genetic disease or only carrying disease-causing mutation, they can use PGT-M to blocks these familial mutations of single-gene defects.
For couples with single-gene genetic disease, there is a 25%-50% probability to give birth to a child with the same single-gene genetic disease through natural pregnancy. In the end, they have to induce labor, which will cause serious physical and mental harm to the couple.
In order to avoid the risk of induced labor and the harm, you can consider the PGT-M to select normal embryos (not carrying the pathogenic mutation of single-gene genetic diseases) to implanted, so as to give birth to healthy babies.
1 Monogenic inherited disease: couples carrying high risk of having offspring with single-gene inherited diseases, or clearly diagnosed of the disease-causing gene mutation
2 Serious diseases with genetic susceptibility: such as the BRCA1/BRCA2 pathogenic mutations of inherited breast cancer
3 Human Leukocyte Antigen (HLA) Matching
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